hrp0097p1-481 | Fetal, Neonatal Endocrinology and Metabolism | ESPE2023

Treatment of Transient Hypothyroxinaemia Of Prematurity may improve premature newborns’ neurodevelopment. NEOTHYR, a multicentered retrospective cohort study about 373 subjects.

Bardet Angélique , Vincent Marine , Bretones Patricia

Background: Transient hypothyroxinaemia of prematurity (THOP), defined as low levels of FT4 without the expected TSH surge, may concern up to 50% of infants born <30 weeks’ gestational age. Most studies showed a link between THOP and impaired neurodevelopment, as shown in the review of Eerdekens. Data about the benefit of supplementation are scarce, with few randomised trials and inconclusive results. To date, there are no clear recommendations regard...